Species-specific dechlorane plus isomer fractionation during bioaccumulation: phenomenon and potential mechanisms

The occurrence and behavior of dechlorane plus (DP), an additive chlorinated flame retardant, have been intensively studied since it was identified in 2006. commercial products DP are a mixture two stereoisomers: syn-DP anti-DP. Stereoselective bioaccumulation isomers biota reported field monitoring laboratory experiments. This review summarizes stereoselective samples provides the potential mechanisms for this bioaccumulation. enrichment widely observed fish, whereas selective anti-DP mainly found some birds. species-specific might reflect that different types isomer fractionation occurred between ectotherms endotherms. Anti-DP is more readily metabolized through biotransformation all animals. However, preferential excretion fish birds based on available data. Both processes determine A direct comparison composition biological conducted most studies to enrichment, which may lead underestimating organisms. factors affected organisms included tissues or organs used, concentration, organisms’ trophic levels occupied, sex. Inconsistent results were obtained considering effects these influence factors. underlying cause inconsistent unclear present Further research interactions biomacromolecule needed.